If an ape can make a discovery, so can you.
Richard P. Feynman
as quoted in this book
What do you think about this quote?
Richard Hamming in his famous talk You and Your Research offers superb advice on how to do great science.
Further advice can be found in the other posts on this blog, e.g. here and here. Also, there are two recent followup papers (On the Process of Becoming a Great Scientist and Ten Simple Rules for Doing Your Best Research, According to Hamming) that could be of some interest.